Rabu, 16 Juli 2014

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Meyler's Side Effects of Antimicrobial Drugs (Meyler's Side Effects of Drugs), by J. K. Aronson

Elsevier now offers a series of derivative works based on the acclaimed Meyler’s Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing biomedical researcher and/or clinician.

This volume is essential for internal medicine physicians and general practitioners who prescribe antibiotic drugs, like penicillin and tetracycline that cure bacterial infections, and antiviral drugs used to treat patients with HIV and herpes viruses.

* The only drug guide that includes clinical case studies and expert analysis
* UNIQUE! Features not only antimicrobial drugs, but also all other drugs that act in an anti-microbial manner
* Most complete cross referencing of drug-drug interactions available
* Latest content from the most highly regarded compilation of drug side effects: Side Effects of Drugs Annual serial

  • Sales Rank: #2614669 in eBooks
  • Published on: 2009-11-27
  • Released on: 2009-11-27
  • Format: Kindle eBook

About the Author
Dr Jeffrey K. Aronson is a consultant clinical pharmacologist and physician in the Department of Primary Health Care in the University of Oxford and a consultant physician in the Oxford Radcliffe Hospitals Trust. He has been associated with the Meyler series since 1977 and has published many research papers on adverse drug reactions. He is President of the British Pharmacological Society and serves on many committees concerned with drug therapy, including the Technology Appraisal Committee of the UK’s National Institute for Health and Clinical Excellence (NICE) and the Joint Formulary Committees of the British National Formulary and the British National Formulary for Children.

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Selasa, 15 Juli 2014

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The Kimchi Cookbook: 60 Traditional and Modern Ways to Make and Eat Kimchi, by Lauryn Chun, Olga Massov

A DIY cookbook for crafting and cooking with kimchi at home, building on the pungent Korean Pickle's recent rise to stardom among top chefs, adventurous eaters, and connoisseur's of fermented, live-culture foods.

Korea’s legendary condiment is taking America by storm with its vibrant, versatile balance of flavor and just the right amount of spice. Making kimchi is the next frontier for anyone who enjoys DIY food projects, and homemade kimchi is a must-have for connoisseurs of the beloved Korean pickle.

Following traditional kimchi-making seasons and focusing on produce at its peak, this bold, colorful cookbook walks you step by step through how to make both robust and lighter kimchi. Lauryn Chun explores a wide variety of flavors and techniques for creating this live-culture food, from long-fermented classic winter kimchi intended to spice up bleak months to easy-to-make summer kimchi that highlights the freshness of produce and is ready to eat in just minutes. 

Once you have made your own kimchi, using everything from tender and delicate young napa cabbage to stuffed cucumber, you can then use it as a star ingredient in Chun’s inventive recipes for cooking with kimchi. From favorites such as Pan-Fried Kimchi Dumplings and Kimchi Fried Rice to modern dishes like Kimchi Risotto, Skirt Steak Ssam with Kimchi Puree Chimichurri, Kimchi Oven-Baked Baby Back Ribs, and even a Grilled Kimcheeze Sandwich, Chun showcases the incredible range of flavor kimchi adds to any plate.

With sixty recipes and beautiful photographs that will have you hooked on kimchi’s unique crunch and heat, The Kimchi Cookbook takes the champagne of pickles to new heights.

  • Sales Rank: #141900 in eBooks
  • Published on: 2012-11-27
  • Released on: 2012-11-27
  • Format: Kindle eBook

Amazon.com Review
Featured Recipe: Quick Cucumber and Chive Kimchi (Oyi Buchu Gutjori)

Prep time: 20 minutes

Brining time: 5 to 7 minutes

Fermentation: Ready to eat

Yield: 5 cups

Ingredients
  • 8 Kirby, 10 Persian, or 2 large Japanese or English cucumbers, unpeeled
  • 2 tablespoons kosher salt (preferably Diamond Crystal)
  • 2 tablespoons Korean chili pepper flakes (gochugaru)
  • 2 teaspoons anchovy sauce (optional)
  • 1-1/2 teaspoons sugar
  • 1/4 cup Korean or regular chives, cut into 2-inch pieces
  • 2 tablespoons thinly sliced onion
Directions

Halve the cucumbers lengthwise, then cut them into 1/8-inch thin diagonal slices. In a medium bowl, mix the cucumbers with the salt until well combined. Set aside for 5 to 7 minutes until cucumbers sweat and glisten. They will lose the some firmness, but should still have a little crunch as you don't want them to be too soft.

Place the cucumbers in a colander and rinse, then pat them dry. In a medium bowl, combine the cucumbers with the chili pepper flakes, anchovy sauce, and sugar and allow to combine for 10 minutes. Add the chives and onion and toss to combine. Eat immediately, or refrigerate and consume within 2 to 3 days.

Review
"[Lauryn Chun’s] primer, The Kimchi Cookbook, takes the traditional Korean condiment to new heights, showcasing its versatility as both a simple pickled vegetable and complex flavor enhancer."
—New York Daily News
 
"Chun's book has a recipe for just about any type of kimchi you could think of, from spicy napa and daikon blends to more creative and modern pickles made from butternut squash, French butter radishes, and even tomatoes. Anyone familiar with Chun's New York-based kimchi company, Mother-in-Law's Kimchi, should be pleased to find many of her signature recipes tucked throughout the book. On top of all of the pickle recipes, Chun also includes about two dozen recipes for using up all those jars of kimchi you'll accumulate, since eating kimchi straight from the jar (no shame) may eventually grow old." 
—Serious Eats
 
"The Kimchi Cookbook: 60 Traditional and Modern Ways to Make and Eat Kimchi is a beautifully photographed, easily readable collection that not only takes on the kimchi we all know and love--made from Napa cabbage, radishes, and the like--but also weaves in Chun's tale of growing up in the culture."
—OC Weekly
 
"Korean culture and cuisine have clearly gone mainstream, so the timing seems perfect for the release of Lauryn Chun’s The Kimchi Cookbook…which highlights the versatility of Korea’s omnipresent spicy fermented vegetable dish." 
—Los Angeles magazine

“If you thought that cabbage was the be-alland end-all of kimchi, Lauryn Chun will quickly prove you wrong. From the quick satisfaction of Cucumber and Chive Kimchi to long-aged bachelor radishes, this book will have you fermenting every season’s vegetable crop, and then show you inventive ways to cook with what you make.”
—Willy Blackmore, Los Angeles editor of TastingTable.com
 
“As an enthusiastic kimchi eater, I’ve long wished for someone to teach me how to create all those interesting, zippy flavors at home. The Kimchi Cookbook is just the thing for home canners who want to take their food preservation beyond traditional jams and vinegar pickles. Lauryn Chun’s recipes for tangy, bright, and bubbly kimchi are approachable and make a world of fermented foods seem firmly within our grasp.”
—Marisa McClellan, author of Food In Jars and creator of FoodInJars.com

About the Author
LAURYN CHUN is the founder of Mother-in-Law’s Kimchi, a line of artisan kimchi based on an original recipe from Jang Mo Jip (“Mother-in-Law’s House”), her mother’s beloved restaurant in Garden Grove, California. From her mother’s kitchen to work in the fine dining and wine industries, Chun’s deep love for food and wine led her from the Rhône Valley and Spain to Italy’s hills, where she worked harvesting grapes. While living in New York City, she recognized the beauty of Korea’s tradition of handcrafted kimchi, which inspired her to launch Mother-in-Law’s Kimchi in 2009.
 
OLGA MASSOV is a Brooklyn-based food writer whose blog, sassyradish.com, has been recognized by Serious Eats, Saveur, theKitchn.com, Smithsonian, and the Huffington Post, among others. Her love of kimchi and fish sauce knows no bounds.

Most helpful customer reviews

56 of 58 people found the following review helpful.
DELICIOUS, PUNGENT, TASTY!
By Cookbookaddict
I wish I could say that I have tried many recipes in this book but the first one I tried was so amazing that I have made it now 3 times and have had trouble keeping my production up with my consumption. The recipe I tried first and keep making is for the cut up fermented kimchi using napa cabbage. If that is the only recipe I get to, this book will have been well worth its price. I have been fermenting for a few years now and have made napa cabbage kimchi before but the flavoring of this kimchi is so perfect for me such that I have not been tempted to tweak the recipe. I was tempted to tweak it the first time I made it since I thought it called for too much onion, but I was so wrong. It mellows during the fermentation process. This book has an excellent ingredient section that is very helpful in explaining the asian ingredients. It is not the best book, however, for someone who has never fermented vegetables before. For that person I highly recommend a book by Sandor Katz. I see that Amazon is selling The Kimchi Cookbook in combination with a Sandor Katz book which might be a good choice. For vegetarians, the author has substitutions for the non-vegetarian umami ingredients in the recipes. I live in a city with a number of asian markets and still some of the ingredients were hard to find (or for me to identify because labels are not usually in english and store clerks rarely speak english) but nonetheless I was able to obtain them. Also, pretty much everything is available on the internet now. If you are in an area where asian ingredients are hard to find I recommend getting the course ground Korean red pepper from Amazon. Substitutes for the Korean red pepper will not do. Happy fermenting!

31 of 31 people found the following review helpful.
Excellent and thorough! Author is a great teacher!
By I Do The Speed Limit
This book is way more than I expected. For a single-topic cookbook I anticipated a straightforward compilation of kimchi recipes. But this book far exceeded my expectations: The author has a very personable style of writing. By the time I was done reading through the pages the first time, I felt a certain satisfaction that is hard to explain. My senses were heightened and my brain was working through the logistics of how soon I could make a trip to my favorite Asian market. And I was wondering if it was too late to plant Red Holland peppers in my garden this year.

If you thoroughly read this woman's instructions, you will have no problem making kimchi. If you have a fear of fermentation, it will be alleviated with the full-coverage instructions and tips in this book. And the information provided is smooth-flowing and easy to digest. The book provides so much worthwhile information, that after you have a few recipes under your belt, you will be experimenting with other ingredients and flavors to create your own signature kimchi.

The recipes area all encompassing; some are for fast, immediate salad-type kimchi; some for Spring and Summer vegetables, and some for winter vegetables. Plus there are instructions for the different "cuts" of the vegetables, and some recipes that keep the vegetable somewhat intact and some recipes for square-chopped veggies.

Pictures are of excellent quality and very helpful, too. Pantry items necessary to make kimchi are relatively few and are fully explained. Both English and Korean names are provided, so it will be easy to find them at your local Asian market or online.

I picked this book up at my library, but today I ordered my own copy. If you are at all interested in eating kimchi, this is a book that has great value and will quickly earn its space on your bookshelf.

12 of 13 people found the following review helpful.
kimchi
By Reisenlauer686
Concise and thoughtfully written, beautiful pictures. Warm personal tone compliments the recipes, and reflects Korean culture. Good book for devotees (fanatics/addicts) of pickled funky deliciousness. Goes well with Sandor Katz's fermentation books.

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Atom Interferometry, by Paul R. Berman

The field of atom interferometry has expanded rapidly in recent years, and todays research laboratories are using atom interferometers both as inertial sensors and for precision measurements. Many researchers also use atom interferometry as a means of researching fundamental questions in quantum mechanics.

Atom Interferometry contains contributions from theoretical and experimental physicists at the forefront of this rapidly developing field. Editor Paul R. Berman includes an excellent balance of background material and recent experimental results,providing a general overview of atom interferometry and demonstrating the promise that it holds for the future.

Key Features
* Includes contributions from many of the research groups that have pioneered this emerging field
* Discusses and demonstrates new aspects of the wave nature of atoms
* Explains the many important applications of atom interferometry, from a measurement of the gravitational constant to atom lithography
* Examines applications of atom interferometry to fundamentally important quantum mechanics problems

  • Published on: 1997-01-08
  • Released on: 1997-01-08
  • Format: Kindle eBook

Review
"I know of no similar books in the literature, and I am sure Atom Interferometry will be very useful for scientists who are interested both in the fundamental and applied aspects of quantum physics."
--Vasili Kharchenko, Harvard-Smithsonian Center for Astrophysics, PHYSICS TODAY.

From the Back Cover
In the past several years, there have been many important developments in the rapidly emerging field of atom interferometry. Atom interferometers have been constructed by several research groups around the world and used both as inertial sensors and for precision measurements. Also, atom interferometers allow researchers to probe interesting fundamental questions in quantum mechanics. This volume contains contributions from theoretical and experimental physicists at the forefront of these developments. There is a balance of background material and recent results that will enable the reader to acquire both a general overview of atom interferometry and an appreciation of the promise it holds for the future.

About the Author
Dr. Paul Berman is currently Professor of Physics at the University of Michigan. He is a Fellow of the American Physical Society, and a member of the Optical Society of America. Nonlinear spectroscopy, atomic physics, quantum optics, and atom interferometry are the major fields of Dr. Berman's research. Academic Press published one other book by this author, Cavity Quantum Electrodynamics (1995).

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For a reader unfamiliar with the history of Libya, Muammar Qaddafi might be mistaken for a character in fiction. His eccentric leadership as the nation's "Brother Leader," his repressive regime, sponsorship of terrorist violence, unique vision of the state, and relentless hold on power all seem implausibly extreme. This riveting book documents the extraordinary reality of Qaddafi's rise and 42-year reign. It also explores the tenacious popular uprising that finally defeated him and the possibilities for Libya as the future unfolds.

Alison Pargeter, an author with deep understanding of Libya's history and people, explains what led up to Qaddafi's bloodless coup in 1969 and how he proceeded to translate his highly personalized vision into political, economic, and social policy. She discusses his tight-knit networks, the crises he overcame—including sanctions after the Lockerbie bombing in 1988—as well as his astounding maneuverings in the early 2000s to restore tattered relations with the West. Pargeter provides a thoroughly fascinating analysis of the 2011 revolt and uncovers the full details of Qaddafi's downfall. She concludes by introducing the new power brokers in post-Qaddafi Libya as well as the variety of knotty challenges that now confront them.

  • Sales Rank: #803488 in eBooks
  • Published on: 2012-06-27
  • Released on: 2012-06-27
  • Format: Kindle eBook

Review
“In this timely reflection on one of recent history’s most outlandish demagogues, Pargeter follows Qaddafi as he seized power through a 1969 military coup, rebelling against the Western-backed king and his paternalistic system. . . . Her informed analysis contextualizes the long-fermenting stew of oppression and anger that was to finally erupt in civil war, and addresses the challenges the National Transitional Council faces as it struggles to rebuild a nation.”—Publishers Weekly (Publishers Weekly)

“Her account is well-researched and draws upon direct observation. She keeps the story moving and asks the right questions: how did Gaddafi remain in power for so long, why did his end come as it did, and can Libya now be turned into a functioning state?”—Nicholas Hagger, European Quarterly (Nicholas Hagger European Quarterly 2016-02-01)

About the Author
Alison Pargeter is an analyst and writer specializing in North Africa and the Middle East. She has held academic positions at the University of Cambridge and Kings College, London, and is a senior associate at Menas Associates, an international research consultancy. She is the author of The New Frontiers of Jihad: Radical Islam in Europe and The Muslim Brotherhood: The Burden of Tradition.

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5 of 6 people found the following review helpful.
Western policy makers regarding Libya should read this book
By John Allnutt
This is a very timely study of the Qaddafi regime's 42 year dictatorship. There have been several books about Libya while Qaddafi was in power but none boldly predicted when or how his regime would end. The arc of Ms. Pargeter's book is a cleanly written objective and historical account of the Qaddafi regime and its October 2011 demise when Qaddafi was found and summarily executed.
The book describes the various empires since ancient times that controlled the region we know as Libya. It then identifies the social, economic and political conditions following the end of World War II that would lead to an atmosphere ripe for Qaddafi's 1969 bloodless coup.
We are taken through the 1970s and 1980s and the Qadhafi regime's social experimentation, nationalization of industry, expulsion of Westerners and his pursuit of Gamal Nasser's Pan Arabism dream. Ms. Pargeter walks us through Qadhafi's foreign adventurism, particularly his efforts to make Libyans world-wide fear his wrath for criticism of his rule; his use of terrorism as a foreign policy tool and his ultimate confrontation with the United States and the West.
Ms. Pargeter continues the timeline into the 1990s when the West continued to treat his regime as a pariah state until Qadhafi allowed the turnover of the indicted suspects in the bombing of Pan Am 103 (otherwise referred to as the Lockerbie bombing). Ms. Pargeter also describes Qaddafi's efforts at "reform" since it appeared after 30 years of ruling he still had no fully content, obedient, happy population always willing to keep him in power. But the reform was always a ruse. Qaddafi's very westernized son Saif frequently campaigned in European circles that his father was going to allow more economic and political freedom. But it was always clear (to both Ms. Pargeter and an assortment of other Libya watchers) that Qadhafi was not going to allow any freedom that threatened his grip on power. And when the rattling of freedom protests became too loud in February 2011, Saif Qaddafi threw in his lot with his oppressive father and sealed the fate of both of them.
Although the book is less descriptive about the US-Libyan confrontation between 1980 and 1991 - and one can get more detail and explanation in other books about that bellicose relationship - it is, nevertheless an invaluable study of a country rich in oil and of economic interest to the West. Libya: The Rise and Fall of Qaddafi was released in early August 2012, a month before the terrorist attack on the US Mission in Benghazi. Because she describes the power vacuum in Libya since the demise of the Qaddafi regime, readers are afforded an opportunity to better understand the state of Libya before advocating an enormous Western intervention. Ms. Pargeter's primer should be required reading in the oil industry, as well as diplomatic, intelligence and military circles, in the United States and the UK.

5 of 6 people found the following review helpful.
Libya - Pargeter
By Brian Dominic D'Monte
excellent - a very well-written and interesting account of a country I lived in and enjoyed for more than two years; well-recommended to any one who has misconceptions about this terrific country

3 of 4 people found the following review helpful.
An excellent primer on post-independence Libya
By Mike V.
Libya: The Rise and Fall of Qaddafi begins by covering a brief history of Libya and some of the events that shaped its society and culture up to independence in the aftermath of WW2. It then goes into the benefits and downfalls of King Idris, the monarch who ruled prior to Qaddafi. The meat of the book is dedicated to covering, as the name suggests, the rule and deposing of Colonel Muammar Qaddafi. The book breaks this into sections that cover the first decade of his rule and the various social, political, and economic changes he tried to institute. It then goes on to discuss his era of foreign policy clashes in the Middle East, Africa, and with the West. From there it talks about the crises that occurred in the late 1980's and 1990's as sanctions, a strong Islamic resurgence, and Qaddafi's inability to rule the country on any more than a whimsical level stressed the foundations of the country. Finally, the book covers Qaddafi and his families attempt to hold on to power with various attempts to bring the appearance of reform to the regime to both attract foreign investment and to stave off dissent at home. The last chapter covers the Arab Spring revolution that ousted him and the various impediments the new leaders have faced to creating a more united and democratic country in spite of Qaddafi's legacy that continues to loom over the populace.

This book is an great introduction for those interested in learning more about Libya post-independence and it's affect on the North African region. It is, by-and-large very well written and easy to read. This book only took me several days to get through, but gave me a good understanding of the general swath of Libyan history since 1945. It is certainly not aimed at an expert audience, but nor does it dumb down things too heavily either. The author does not reach any really ground-shaking conclusions (at least that I noticed), but instead succeeded in bringing an up-to-date, fairly comprehensive, and most importantly, cogent account of Libya's modern history to the marketplace.

Recommended for amateur historians looking for something outside their usual area of interest and those looking to learn a bit more about one of the countries overtaken in the Arab Spring.

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Pincer complexes are formed by the binding of a chemical structure to a metal atom with at least one carbon-metal bond. Usually the metal atom has three bonds to a chemical backbone, enclosing the atom like a pincer. The resulting structure protects the metal atom and gives it unique properties.

The last decade has witnessed the continuous growth in the development of pincer complexes. These species have passed from being curiosity compounds to chemical chameleons able to perform a wide variety of applications. Their unique metal bound structures provide some of the most active catalysts yet known for organic transformations involving the activation of bonds. The Chemistry of Pincer Compounds details use of pincer compounds including homogeneous catalysis, enantioselective organic transformations, the activation of strong bonds, the biological importance of pincer compounds as potential therapeutic or pharmaceutical agents, dendrimeric and supported materials.

* Describes the chemistry and applications of this important class of organometallic and coordination compounds
* Covers the areas in which pincer complexes have had an impact
* Includes information on more recent and interesting pincer compounds not just those that are well-known

  • Published on: 2011-08-11
  • Released on: 2011-08-11
  • Format: Kindle eBook

About the Author
David Morales Morales carried out his B.Sc. (1992) and M.Sc. (1995) studies at the School of Chemistry of the Universidad Nacional Autónoma de México (UNAM). In 1995 he was awarded a scholarship by the Mexican Government to carry out Doctoral studies at the University of Essex (UK) under the supervision of Prof. Jonathan R. Dilworth. In 1997, he moved to the "Inorganic Chemistry Laboratory" at the Oxford University (UK), getting his Doctorate in 1998. In the same year Prof. Morales-Morales was offered a posdoctoral position by Prof. Craig. M. Jensen in the Department of Chemistry of the University of Hawaii at Manoa, USA. Where he carried out research relevant to the development of a new generation of PCP pincer complex and their use in C-H activation and C-C bond formation. Beneficiary of the National Program for Repatriation of the National Science and Technology Council (CONACyT-México), Prof. Morales-Morales works since May 2001 as a researcher at the Instituto de Química-UNAM. His research interests include 1) The Chemistry of Pincer Compounds; 2) Synthesis of phosphorus and sulphur base compounds and its use as ligands with transition metals; 3) Metal Mediated Organic Synthesis and 4) Mechanistic Studies. Prof. Morales-Morales has a total of 60 papers and a chapter in the book "Modern Coordination Chemistry", edited by the Royal Society of Chemistry (2002). More recently he has served as editor of the Book "The Chemistry of Pincer Compounds" Edited by Elsevier and a co-authored a text Book on Organometallic Chemistry Edited in Spanish by UNAM. He belongs to Chemistry Societies in Mexico and the United States. Prof. Morales-Morales has been visiting Professor at the Instituto de Materiales de Aragón-CSIC (Zaragoza, Spain), The Anorganisch-Chemisches Institut der WWU Münster in Germany and the Metal Mediated Synthesis - Debye Institute at the University of Utretch (Netherlands). In various campus of the University of California (Riverside, San Diego and Sa

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A concise, easily accessible introduction to descriptive and inferential techniques

Statistical Inference: A Short Course offers a concise presentation of the essentials of basic statistics for readers seeking to acquire a working knowledge of statistical concepts, measures, and procedures.

The author conducts tests on the assumption of randomness and normality, provides nonparametric methods when parametric approaches might not work. The book also explores how to determine a confidence interval for a population median while also providing coverage of ratio estimation, randomness, and causality. To ensure a thorough understanding of all key concepts, Statistical Inference provides numerous examples and solutions along with complete and precise answers to many fundamental questions, including:

  • How do we determine that a given dataset is actually a random sample?
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The book is organized to present fundamental statistical concepts first, with later chapters exploring more advanced topics and additional statistical tests such as Distributional Hypotheses, Multinomial Chi-Square Statistics, and the Chi-Square Distribution. Each chapter includes appendices and exercises, allowing readers to test their comprehension of the presented material.

Statistical Inference: A Short Course is an excellent book for courses on probability, mathematical statistics, and statistical inference at the upper-undergraduate and graduate levels. The book also serves as a valuable reference for researchers and practitioners who would like to develop further insights into essential statistical tools.

  • Sales Rank: #2057060 in eBooks
  • Published on: 2012-06-06
  • Released on: 2012-06-06
  • Format: Kindle eBook

Review

“The book is addressed to courses on probability, mathematical statistics, and statistical inference at the upper-undergraduate and graduate levels. It also serves as a valuable reference for researchers and practitioners who would like to develop further insights into essential statistical tools.”  (Zentralblatt Math, 1 August 2013)

“If an undergraduate student seeks a guide that will introduce the basic ideas of statistics, or a lecturer wants interesting life examples and a source of valid intuitions to improve his teaching skills, then this book is a great place to start. . . This book, with its explanations of basic intuitions, its many examples, the easy language, and a minimal requirement for mathematical training, is a good self-contained starting point to prepare one for the jump into those heavier works.”  (Computing Reviews, 30 September 2013)

About the Author

MICHAEL J. PANIK, PhD, is Professor Emeritus in the Department of Economics at the University of Hartford. He has served as a consultant to the Connecticut Department of Motor Vehicles as well as a variety of healthcare organizations. Dr. Panik has published numerous journal articles in the areas of economics, mathematics, and applied econometrics.

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0 of 1 people found the following review helpful.
Five Stars
By sanem aytas
Half of the back page answers are wrong, be careful when you study.

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Five Stars
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Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike.



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  • Sales Rank: #2159330 in eBooks
  • Published on: 2012-07-26
  • Released on: 2012-07-26
  • Format: Kindle eBook

Review

"This volume constitutes a comprehensive survey of the emerging field of epigenetics in the etiology, progression, diagnosis, prognosis and treatment of human diseases… With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike."--Anticancer Research, Volume 33, Issue no. 5, May 2013 "This book covers a huge range of topics, from early life effects on adult disease to epigenetic changes occurring with aging and senescence. Especially pertinent are the several chapters on epigenetic treatments for disease including drugs, miRNA/siRNA, natural substances and foods. With up to date coverage of an ever expanding field, Epigenetics in Human Disease will be a great resource for clinicians, researchers and students."--Craig Cooney, Investigator, Research Service, Veteran's Affairs Medical Center, Little Rock, AR & Affiliate Scientist, Nanotechnology Center, University of Arkansas, Little Rock, AR

About the Author
Professor of Biology, University of Alabama at Birmingham, Birmingham, AL. Dr. Tollefsbol is a Professor of Biology and a Senior Scientist in the Center for Aging, Comprehensive Cancer Center, Nutrition Obesity Research Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999 and a Steering Committee Member of the UAB Center for Aging. Dr. Tollefsbol trained as a Postdoctoral Fellow and Assistant Research Professor with members of the National Academy of Science at Duke University and the University of North Carolina. He earned doctorates in molecular biology and osteopathic medicine from the University of North Texas Health Sciences Center and his bachelor’s degree in Biology from the University of Houston. He has received prior funding from the NIA, NCI, NHLBI, NIMH and other federal institutes as well as the Glenn Foundation for Medical Research, Susan G. Komen for the Cure, the American Federation for Aging Research (AFAR), and the American Institute for Cancer Research (AICR) among many other sources. The Glenn Foundation for Medical Research funding was unsolicited and was awarded to Dr. Tollefsbol for lifetime contributions to the field of aging. In 2006 Dr. Tollefsbol was selected and highlighted as part of the 25th anniversary of the AFAR for significant contributions to aging research. Dr. Tollefsbol’s research interests have covered a wide range of topics such as aging, epigenetics, nutrition, cancer, telomerase, and caloric restriction. Work from his laboratory has been featured in Women’s Health magazine, Shape magazine, and the AICR Newsletter and Dr. Tollefsbol has been a Scientist in the Spotlight in ScienceNow. Currently he serves as an Associate Editor for Frontiers in Epigenomics and is on the Editorial Boards of the international journals Open Longevity Science, Epigenetics of Diabetes and Obesity, Molecular Biotechnology and Clinical Epigenetics. He is also a contributing Editor of Lewin’s GENES X classic textbook. Over 25 of the publications from Dr. Tollefsbol’s laboratory have received national or international accolades such as best paper award, selection for press release by the journal editors and featured on the journal homepage. Dr. Tollefsbol has been invited to give presentations on his research in many countries including Germany, China, Italy, Switzerland, France and The Netherlands as well as at various leading institutions in the US such as Harvard Medical School, Tufts University and the University of California at San Francisco. His research has received considerable media attention both nationally and internationally through television, newspaper and radio venues and has been highlighted in eScience News and ScienceDaily. He has ten books which have been published or are in progress and a recent book on “Epigenetics of Aging” that Dr. Tollefsbol co-authored and edited was highlighted in Nature.

Most helpful customer reviews

3 of 3 people found the following review helpful.
Considerable Detail But Lacks Overviews
By Dr. Terrence McGarty
Epigenetics is an expansive text by multiple authors covering an exploding field. The text manages to address all the key issues by examining the state of the literature. It deals with non coding RNAs including miRNA and lncRNAs and deals with methylation across DNA and acetylation on histones. It looks at cancers and others diseases and its span of the literature is superb. In essence, it is a wonderful review of the literature.

On the negative side it totally lacks an overview for the less attuned reader. One must somewhat fully understand methylation first before approaching this book. Then and only then do you have a platform to explore the wealth of information contained within the book.

The multi-author approach has positives and negatives. On the one hand the authors present world-class material useful for those looking to explore niches of epigenetics. On the other hand it tends to lead to a disparate set of chapters with no cohesive core.

For those in the field this is highly valuable and is well worth the purchase. However for those newly exploring the area this is a difficult first introduction.

0 of 0 people found the following review helpful.
outstanding in clarity,comprehensiveness and ease of navigating
By Willem Lake
sound scientific treatise of a very new field of research. It is a pleasure to read and the drawings are clear and comprehensive

See all 2 customer reviews...

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